Diminish fine lines and wrinkles and achieve smoother firmer and more evenly toned skin. This refining Retinol treatment is enhanced with a revolutionary, time released delivery system along with the antioxidant benefits of 90% Green Tea Polyphenols and Caffeine USP to help prevent irritation while efficiently delivering results. Directions: Avoiding eye area , apply to clean skin once daily in the evening or as directed by Dr. Emami. Ingredients: All-trans- Retinol and Green Tea Polyphenols- studies show they work synergistically to build up the skin matrix. Caffeine- enhances overall antioxidant activity, helps diminish the appearance of redness.